Popular Minoxidil: Definitive Guide

Minoxidil: Definitive Guide

Minoxidil is an antihypertensive vasodilator drug commonly used for the treatment of moderate intensity androgenic alopecia and for severe cases of hypertension.

The origins of minoxidil as a drug date back to 1979, when it was discovered, the compound was a powerful vasodilator and was indicated for patients with kidney problems who were resistant to other medications. During clinical use, it was perceived that male patients experienced increased body hair and beard, on the other hand, in some women hypertrichosis, also known as werewolf syndrome, developed; It is a very rare disease, and is distinguished by the existence of excess hair. This unexpected side effect led to the investigation of its use for the treatment of baldness.

Minoxidil treatment. 

El minoxidil It is the most widely used medicine to treat problems of falling hair

Hair loss or alopecia It is a very common problem that affects a significant percentage of the population. 

La androgenetic alopecia It is the most common type of alopecia. It mainly affects men, however, women can also suffer from it. 

In the case of men, after 50 years, up to half have some degree of alopecia. 

From a medical point of view, the androgenetic alopecia It is not a disease that puts people's lives or body function at risk. 

That is why most people who suffer from it first seek some home remedy or alternative treatment, before seeking advice from a expert doctor

Androgenetic alopecia is similar behaves like a chronic conditiontherefore, constant medical treatment is required to stop the fall process. 

El minoxidil It is one of the most widely used medications to treat hair loss problems. 

What is minoxidil?

Minoxidil works primarily as a vasodilatador. That is, it causes the blood vessels to relax and increases blood flow to body tissues

It was originally developed for use in the treatment of high blood pressure. However, it was observed that a significant percentage of the patients who used it had undesirable hair growth. 

Noticing I had that "adverse effect"Many doctors started using it to treat hair loss problems. Because oral treatment caused many adverse effects, it was tried to administer it topically directly on the scalp. The results were so satisfying that the United States FDA approved it as a treatment for hair loss problems. 

How does minoxidil work?

Scientists are still not 100% sure how minoxidil causes hair growth. In fact, its original use was to lower blood pressure; However, a side effect was hair growth. Scientists say it stimulates blood circulation in the hair follicles. And better blood flow means more hormones and nutrients reach the hair roots and stimulate growth.

In its most fundamental sense, minoxidil prolongs the Anagen phase of hair cells. There are three hair growth phases: Anagen, Catagen and Telogen, and during the Anagen phase is when the hair grows. A shortened Anagen phase means less hair growth.

Minoxidil also stimulates an enzyme called prostaglandin synthase-1 through the immune system. Many scientists believe that hair loss has a connection to changes in the immune system.

Minoxidil Presentations


Minoxidil foam is the most popular type used for hair loss. It is more expensive than liquid minoxidil, but it dries twice as fast.


The liquid is the original form of minoxidil / Rogeine used for hair loss. It is less expensive than foam, but takes longer to dry. You can apply it twice a day.

So Minoxidil has FDA approval and proven results. What is the trap? Well, again, it is not a permanent solution and you should continue applying it, in most cases, twice a day, as part of your daily routine. Some minor side effects include:

  • Dry skin: dry skin is more frequent when using the liquid version.
  • Fast or irregular heartbeat.
  • Low Blood Pressure: That is not a big surprise considering that Minoxidil started as a medication to treat high blood pressure. Just be careful that your blood pressure doesn't drop too low. Also, don't use it as a substitute for your regularly prescribed blood pressure medication.
  • Potential Weight Gain: Weight gain has been mentioned by some patients as a possible side effect of Minoxidil, but weight gain is often due to many factors, including lifestyle and diet.

Why does minoxidil work?

Minoxidil increases blood flow to the areas where it is applied. Applying it to the scalp increases blood flow and therefore the follicles receive more oxygen and nutrients. Minoxidil increases the progression and duration of the anagen phase of the follicles, which is the phase of active hair growth. Other studies suggest that it reduces the duration of the telogen phase, which is the resting phase of the follicles. 

How is minoxidil used?

It is applied topically, in the form of a spray, lotion or shampoo. It must be applied every day, at least twice to be effective. The lotion must be in direct contact with the skin for 4 hours, so that it works properly. So once it is applied, you have to wait that time to be able to wash the area. 

How long will it take to see the results?

When used on a daily basis, results are observed from 6 months. The maximum effect is achieved after one year of treatment. Because minoxidil only stimulates the still viable follicles and does not cause new hair growth, it must be used indefinitely to maintain the effect. 

If the treatment is stopped, the stimulated hair begins to lose after 3-4 months. 

Can women also use minoxidil?

Women can use minoxidil without problem. However, some studies have shown a correlation between minoxidil and the development of fetal malformations. Therefore pregnant women should avoid using it.

Does minoxidil work for the beard?

The use of minoxidil for the beard has become a hot topic and many people want to know if it really works. Some people looking to have a beard, before trying a procedure beard transplant try to use minoxidil.

Minoxidil is an antihypertensive vasodilator drug commonly used for the treatment of moderate intensity androgenic alopecia and for severe cases of hypertension.

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Dr. Enrique Orozco
Dr. Enrique Orozcohttps://dreoclinic.com/
General Director, Specialist in Trichology and Hair Transplantation Certified by ABHRS. Only ABHRS Certified with residence in Mexico.


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Dr. Enrique Orozco
General Director, Specialist in Trichology and Hair Transplantation Certified by ABHRS. Only ABHRS Certified with residence in Mexico.




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